🧠 Computational Neuroscience Lab

Decoding the Mind, Quantified.

Tale Research builds clinical-grade measurement platforms for neuroscience — from a single structural MRI to a real-time EEG, and the modalities beyond. Open methods. Traceable numbers. On-premises by design — built for the reality of clinical environments and the questions that sit between them.

🧭 Products

Measurement instruments for the clinical reality.

Two platforms, one philosophy: build tools that make something invisible visible, keep the data on-premises, and leave every clinical decision with the practitioner.

NeuroSentinel

The brain, measured — one scan at a time.

NeuroSentinel turns a single 3D T1 MRI into a structured volumetric read: 104 Desikan-Killiany brain regions, age- and sex-matched percentile scores against a 205-subject open normative cohort, a traumatic-injury structural signature, and an interactive WebGL viewer. On-premises, HIPAA-aware, no PHI transmitted.

104 structures Age/sex Z-scores On-prem deployment Browser viewer
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Vexis

See what your hands are doing.

Vexis pairs real-time electroencephalography with the manual therapies practitioners already trust. It surfaces the Vexis Relaxation Index — a single clinically meaningful marker of parasympathetic dominance — and makes the effect of a session visible band by band, second by second.

Real-time EEG Relaxation Index Clinic-local Longitudinal
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Advanced Technology

Scientific Breakthroughs in Neurotechnology

Tale Research integrates cutting-edge neuroscience, advanced mathematics, and artificial intelligence to develop breakthrough brain-computer interface technologies with proven scientific foundations.

🧠

Advanced EEG Signal Processing

Cutting-edge preprocessing and analysis of electroencephalography data using state-of-the-art machine learning techniques optimized for high-dimensional neural signals.

Real-time Processing Artifact Removal Feature Extraction
🤖

Machine Learning for Neural Data

Custom artificial neural network architectures designed specifically for EEG classification, with advanced hyperparameter optimization and cross-subject adaptation.

Deep Learning Cross-Subject Optimization
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Brain-Computer Interfaces

End-to-end BCI system development from signal acquisition to real-world application deployment, enabling direct neural control of external devices.

Real-time BCI Adaptive Systems Low Latency
📊

Dimensionality Reduction

Novel approaches to overcome the curse of dimensionality in high-channel EEG recordings using manifold learning and sparse coding techniques.

Manifold Learning Sparse Coding Feature Selection
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Cognitive State Recognition

Machine learning approaches for recognizing different cognitive states from EEG signals, including attention, mental workload, and emotional states.

Attention Detection Workload Assessment Emotion Recognition
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Research Collaboration

Partnership opportunities for academic institutions and research organizations in computational neuroscience, with proven track record of high-impact publications.

Academic Partners Grant Support Publications
🔬 Research Integrity

Research Excellence

Tale Research is built on a simple commitment: open methods, peer-reviewed components, and numbers that trace back to the image or signal they came from. No proprietary black boxes between raw data and clinical read.

📚 Open, peer-reviewed stack

Built from components anyone can cite.

FreeSurfer SynthSeg for parcellation, MNE-Python for EEG band decomposition, validated PSD methods throughout. The whole stack is published, inspectable, and reproducible — not a proprietary classifier hiding behind a logo.

SynthSeg FreeSurfer MNE-Python
🧭 Traceable from data to read

Every number points back to the voxels or the signal.

Each percentile, asymmetry index, and band-power score traces to the structure or the EEG window it was computed from. Click a region in the report and jump straight to its segmentation in the viewer. No score appears that you can't audit.

104 structures Per-region provenance Auditable scores
📊 Open normative reference

205-subject reference cohort, documented and expandable.

Volumetric percentiles are computed against an open normative MRI cohort with documented inclusion criteria and demographics. Age- and sex-matched. Designed to grow as collaborating sites contribute their own scans.

205 subjects Age & sex matched Expandable
🔒 On-premises, HIPAA-aware

The analysis runs where the data lives.

Both platforms are designed to run inside the clinic or the research network. No PHI leaves the local environment, no patient data is required for licensing, and the deployment fits the constraints IRBs and IT security teams actually have.

On-prem deployment No PHI transmission IRB-friendly
NeuroSentinel multi-plane MRI viewer with structural overlays and 3D head reconstruction
NeuroSentinel · interactive MRI viewer · live platform output

Ready to Advance Neuroscience Research?

Join leading researchers and institutions worldwide who are using our cutting-edge computational neuroscience solutions to unlock new discoveries in brain function and cognition.